The National Toxicology Program (NTP) Chronic Carcinogenicity Studies of Cell Phone Radiofrequency Radiation are the most comprehensive, carefully done studies performed to date on the long term effects of radio frequency radiation from wireless devices such as cell phones. This 10 year, $25 million dollar study was performed by the National Institute of Environmental Health Sciences. Interpretation of the study results varies but the research has demonstrated an increase in tumors of the heart and brain in rodents exposed to cell phone radiation.
Partial results on rat studies were released in May 2016 while the final results discussing effects on mice were released February 2018. Technical report abstracts can be found here TR-595 and TR-596. These studies support an abundance of other research showing a carcinogenic effect of cell phone and wireless radiation from cell towers and the multitude of wireless devices we are exposed to, including cell phones, cordless phones, Wi-Fi and Smart Meters. A Peer review by an expert panel of the NTP Draft Technical Reports will be held March 26-28, 2018 at Research Triangle Park, North Carolina. Details here. Below are some discussions of the science and results. For other scientific literature on a broad range of RF effects go to MDSafeTech.org and look under Scientific Literature or Bioinitiative Report at Bioinitiative.org.
Final NTP Report 2018
The final NTP report was released February 2, 2108. NTP Study Full Report Feb 2, 2018. Although some news media headlines stated the results were not conclusive, the conclusions of the scientists who conducted and reviewed the results were that whole body non-ionizing radiation from cell phone radiation showed:
- An increase in gliomas of the brain and schwannomas of the heart
- An increase of tumors in other organs (adrenal, prostate, pancreas, liver)
- An increase in glial cell hyperplasia of the brain (which is considered a precursor to malignant glioma in the exposed group which is likely turn into malignant glioma. (10-13) No glial cell hyperplasia was seen in the unexposed control groups indicating causation of lesions from RF Radiation.
- DNA Damage from cell phone radiation was also found in both rats and mice. The rat study data was reported at a Sept 9, 2017 annual meeting of the Environmental Mutagenesis and Genomic Society, held in Raleigh, North Carolina. NTP-DNA-Damage-Abstract-from-Sept-2017-EMGS Presentation-
EHTrust Research Presentation on Partial Results. Dr. Linda Birnbaum, Director of the National Institute of Environmental Health Sciences presented the Partial Results of NTP Chronic Carcinogenicity Studies of Cell Phone Radiofrequency Radiation in Rats on Jan 24, 2017 in Jerusalem, Israel at a meeting sponsored by the Environmental Health Trust. Dr. Birnbaum-NTP Study Partial Results Cell Phone Radiofrequency Radiation- The Environmental Health Trust NTP Information page is here.
Dr. Joel Moskowitz reports on the NTP studies and news articles here. He notes a soon to be published rodent study on whole body exposure of radio frequency radiation by Dr. Ramazzini revealing that RFR caused malignant schwannomas of the heart in rats exposed to to 1.8 GHz GSM cell phone radiation for 19 hours per day from prenatal life until natural death. The rat exposures were lower than the NTP study. Dr. Moskowitz notes “The SAR values in this study ranged from 0.001 W/kg to 0.1 W/kg as compared to 1.5 to 6.0 W/kg in the NTP study.” These studies along with many other research studies in the literature indicate that long term exposure to low-level, non-thermal non-ionizing radiation from wireless devises causes and/or contributes to cancer and DNA damage in animals. Considering the many human studies on mutagenic effects of non-ionizing radio frequency radiation, this could translate in to a carcinogenic effect in humans.
Letters from physicians and scientists regarding the final NTP results
Dr. Lennart Hardell, Oncologist, Sweden: Hardell Comments-on-NTP-study March 12, 2018
Dr. Hardell notes in his letter that the results showing an increase in schwannomas and gliomas are of increased concern as it corroborates carefully done epidemiological studies on cell phone use and brain cancer which revealed an increase of similar brain tumors in humans with long term use of cell phones on the ipsilateral (same) side of the head. In the final NTP study researchers also found an increase in malignant lymphomas of all exposed groups compared to controls. Dr. Hardell also notes an increase in thyroid cancers worldwide as well and discussing why the location of cell antennas on phones could account for this increase.
Issues and Information NTP Results
GSM and CDMA, which were the sources of RF radiation used in the study, are 2 variants of second generation (2G) cellular communication technology. GSM (Global Systems for Mobile) is used by AT & T and T-Mobile and most of the world. CDMA (Code Division Multiple Access) is owned by Qualcomm and is used by Sprint, Verizon, US Cellular. GSM phones have a removal SIM card to make it easier to change phones and keep data. We are now exposed to an increased mix of 2G, 3G and 4G radiation frequencies globally. 5G technology is now being promoted to power the Internet of Things.
Issues with NTP Study on Cellphone Radiation and Cancer Presentation June 2016
Issue: Controls in all groups had no cancer
Response: This could indicate that exposure protection from cell phone wireless radiation protects from cancer promotion as the rate of tumors inrodent historical controls are at 2%.
Issue: Female rodents did not develop brain tumors.
Response: There are typically gender differences in rodent studies and it appears through studies that the female brain proves neuroprotection. Gender Differences in Chemical Carcinogenesis in National Toxicology Program 2-Year Bioassays. Sandeep Kadekar. Toxicologic Pathology. May 14, 2012. Gender Differences in Carcinogenic Studies
Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection.Cardona-Gomez. Brain Research. 2001. Estrogen as Neuroprotectant
NTP Study of Hyperplastic and Malignant Brain Lesions Indicate Higher Concern
The separate glial cell hyperplasia seen in the exposed group is likely turn into malignant glioma according to Dr. Wyde, the presenter. They have the same pathology but hyperplastic lesions are smaller in size. Many think the hyperplastic brain lesions need to be added to the malignant brain tumors when evaluating the statistics on brain tumor incidence. Brain tumor results starts at 25:09. Heart Schwannoma results start at 27:09to 28:50. 2016 NTP cell phones and cancer presentation of results
Dr. Wyde, Cell Phone Radiation Cancer Study US NTP presentation
Dr Wyde presents results of the rat studies from the U.S. NTP research on cell phones and cancer. June 2016.
References: 2016 National Toxicology Program NIEHS 10 Year Study on the long term effects of cell phone radiation and cancer.
1) Report of Partial Findings from the National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation in Hsd: Sprague Dawley SD Rats (Whole Body Exposure). May 26, 2016. http://www.biorxiv.org/content/early/2016/06/23/055699
2) NTP Toxicology and Carcinogenicity Studies of Cell Phone Radiofrequency Radiation-Slide Presentation. Michael Wyde, PhD, DABT. National Toxicology Program. National Institute of Environmental Health Sciences. June 8, 2016 https://ntp.niehs.nih.gov/ntp/research/areas/cellphone/slides_bioem_wyde.pdf
3) National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation. May 2016. https://ntp.niehs.nih.gov/results/areas/cellphones/
4) Major Cell Phone Radiation Study Reignites Cancer Questions. Scientific America. May 2016. https://www.scientificamerican.com/article/major-cell-phone-radiation-study-reignites-cancer-questions/
5) Cellphone-Cancer Link Found in Government Study. http://www.wsj.com/articles/cellphone-cancer-link-found-in-government-study-1464324146
6) The NIEHS/NTP Cell Phone Radiation Study: Ronald Melnick PhD Full Interview https://www.youtube.com/watch?v=46TbbcpVfjA
7) National Toxicology Program:Cell Phones. https://ntp.niehs.nih.gov/results/areas/cellphones/
8) TR-595: Toxicology and Carcinogenesis Studies in Hsd:Sprague Dawley SD Rats Exposed to Whole-Body Radio Frequency Radiation at a Frequency (900 Mhz) and Modulations (GSM and CDMA) Used by Cell Phones. Feb, 2018 https://ntp.niehs.nih.gov/results/pubs/longterm/reports/longterm/tr500580/listedreports/tr595/index.html
9) TR-596: Toxicology and Carcinogenesis Studies In B6C3F1/N Mice Exposed to Whole-Body Radio Frequency Radiation at a Frequency (1,900 MHz) and Modulations (GSM and CDMA) Used by Cell Phones. https://ntp.niehs.nih.gov/results/pubs/longterm/reports/longterm/tr500580/listedreports/tr596/index.html
10) Glioblastoma-Initiating Cells: Relationship with Neural Stem Cells and the Micro-Environment. Cancers (Basel). 2013. Goffart N, et al. Sep; 5(3): 1049–1071. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795378/
11) New aspects of glioblastoma multiforme revealed by similarities between neural and glioblastoma stem cells. (2018). Cell Biology Toxicicology. Jan 31, 2018. https://www.ncbi.nlm.nih.gov/pubmed/29383547
12) Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells (2013). Alda B et al. PLoS One. 2013 Oct 14;8(10). https://www.ncbi.nlm.nih.gov/pubmed/24155920
13) The cellular origin for malignant glioma and prospects for clinical advancements (2012). Zong H et al. Expert Rev Mol Diagn. 2012 May;12(4):383-394. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368274/